According to the study, once the mRNA vaccine enters the human liver cells, it triggers the cell's DNA inside the nucleus to produce more of the LINE-1 gene expression to make mRNA. This paper suggested that COVID-19 vaccines that cause antibody production may cause a condition known as antibody-dependent enhancement (ADE). See here for a complete list of exchanges and delays. Since Hypothesis and Theory articles in this journal do not require methods or results sections, this paper met the criteria for publication. "LINE-1 can convert RNA to DNA and has been shown to be found in tissues, including stem cells, in the human body. The Swedish study suggests the vaccine is capable of becoming DNA, which is what the CDC claimed [(accessed on 22 February 2022)]. 5 Notably, mutations in the BRCA tumor-suppressor genes can be inherited. Social media users are falsely claiming that a Swedish study conducted by Lund University found that mRNA COVID-19 vaccines permanently alter human DNA. The CDC says that the COVID-19 vaccines do not change or interact with your DNA in any way, claiming that all of the ingredients in both mRNA and viral vector COVID-19 vaccines (administered in the United States) are discarded from the body once antibodies are produced. The authors also pointed out that this cell line has been shown to have genetic and protein expression differences specific to RNA metabolism (p. 1123). The authors said that they chose to study liver cells as Pfizer had reported that about 18% of the vaccine accumulated in the liver in 30 minutes after mice were Alden M, Falla FO, Yang D, et al. About this website Anti-vaccination and ivermectin proponents have gone bananas over the new study from the Lund University doi: 10.7759/cureus.32361. YDM: This study does not investigate whether the Pfizer vaccine alters our genome. (. Epub 2022 Feb 3. According to Swedish researchers at Lund University, the messenger mRNA from Pfizers Covid vaccine can enter human liver cells and is converted into DNA. This in itself motivates the need for further studies. 2020 Apr 9;3:100051. Five patients (42 percent) were evaluated for liver transplantation because of persistent jaundice, hepatic insufficiency, and/or recurrent cholangitis. We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure. Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Front Immunol. Case presentation: We report a case of hepatic artery occlusion after the first dose vaccination by ChAdOx1nCov-19. Consequently, other than the immunization, there are no permanent changes. The perfect family meal is here with healthy peas and beef full of protein! Microbiol Spectr. Original video "Pfizer Vaccine Becomes DNA in Liver Cells. Second, they measured LINE-1 activity. Federal government websites often end in .gov or .mil. Mandatory vaccinations, the segregation of citizens, and the promotion of inequality in the modern democracy of Greece and other democratic countries in the era of COVID-19. This three-part series was aimed at describing several important aspects of science. The researchers write that the findings warrant a further , ! Lund University , conducted by researchers at Lund University in Sweden and published in a peer-reviewed journal, investigated the effect of Pfizers mRNA COVID-19 vaccine on a human cell line that was derived from liver cancer tissue. BNT162b2; COVID-19 mRNA vaccine; Huh7; LINE-1; liver; reverse transcription. Cells that received no vaccine at all were used for control purposes.The researchers then investigated how different gene expressions in the cells changed over time. This paper is not a research study; it is, at best, a modeling study. The whole process occurred rapidly within six hours. (In-vitro Swedish Study)\r\rAn accepted and published Swedish study demonstrates for the first time the presence of Pfizer-BionTech vaccine DNA in the cell. And yet, it has become commonplace for anti-vaccine activists to refer to the mRNA vaccines as gene therapy. The study authors clarified their research in a Q&A in March after it received significant attention, stating this study does not investigate whether the Pfizer vaccine alters our genome, and that there is no reason for anyone to change their decision to take the vaccine based on this study.. YDM: About 18 percent of the vaccine accumulates in the liver just 30 minutes after the vaccine is injected in mice as reported by Pfizer in EMA assessment report, and therefore we chose to study liver cells. YDM: A previous study from MIT has indicated that the SARS-CoV-2 virus mRNA can be converted to DNA and integrated into the human genome. The product has been, During the foetal stage, a number of so-called cell programs run that are vital to the development of the foetus. Rasmussen also said, cell lines differ from cells in living organisms, and therefore it is important that similar investigations are also studied in humans.. Suggested accounts. Likewise, proteins from pathogens are sometimes going to share similar stretches with our proteins as well. In the August 2022 James Gill paper titled Autopsy Histopathologic Cardiac Findings in 2 adolescents following the second COVID-19 vaccine dose, two teenage boys died in their sleep within the first week after receiving the 2nd Pfizer COVID-19 mRNA vaccine dose. Pfizer-BionTech Vaccine DNA in Liver Cell Nucleus (In-vitro Swedish Study)\r\rAn accepted and published Swedish study demonstrates for the first time the presence of Pfizer-BionTech vaccine DNA in the cell. Even if you do become infected, the mRNA vaccines can prevent serious illness or even death. 2020;586:589593. Let's review.\r\rIf you like this content and want more, I am doing a special lifetime membership offer. is the set of instructions to build and sustain a human being. Finally, as the authors pointed out, expression of LINE-1 has been shown to increase during viral infections, including with SARS-CoV-2 virus. Yau K, Chan CT, Abe KT, Jiang Y, Atiquzzaman M, Mullin SI, Shadowitz E, Liu L, Kostadinovic E, Sukovic T, Gonzalez A, McGrath-Chong ME, Oliver MJ, Perl J, Leis JA, Bolotin S, Tran V, Levin A, Blake PG, Colwill K, Gingras AC, Hladunewich MA. YDM: More research is needed. The persistence of the spike protein in the body raises the prospect of sustained inflammation within and damage to organs which express the spike protein, according to experts atDoctors for COVID Ethics,an organization consisting of physicians and scientists seeking to uphold medical ethics, patient safety, and human rights in response to COVID-19.. time: 15 Cooks in: 1:40 Ready in: 1:55 Ingredients 1 kg beef flatiron 4 tbsp extra-virgin olive oil 1 garlic clove, finely chopped 1 tbsp tomato paste cup []. 2020;383:24392450. Reverse transcription is when DNA is made from RNA, whereas the normal transcription process involves a portion of the DNA serving as a template to make an mRNA molecule inside the nucleus. Both boys were pronounced dead at home. This is the first time that researchers have shown in vitro or inside a petri dish how an mRNA vaccine is converted into DNA on a human liver cell line, and is what health experts and fact-checkers said for over a year couldnt occur. They used different concentrations of the vaccine and multiple timepoints to measure: Some pointed to this paper as proof that COVID-19 vaccines alter DNA. Pfizer did not comment on the studys findings, the Epoch Times reported, stating only that its mRNA vaccine does not alter the human genome. The clip comes from a longer roundtable discussion that was posted March 8 by Christian broadcasting network Daystar, during which faith leaders discussed COVID-19 vaccines with the doctors. The research was conducted at Lund University. Lund Universitymagnus [dot] rasmussen [at] med [dot] lu [dot] se, Yang de Marinis 2023 Jan 19. Thank you for taking time to provide your feedback to the editors. They are not sure if it gets integrated in our DNA or not. The posts share articles such as ones archived (here) and (here) saying the study, which was published in the Current Issues in Molecular Biology, shows mRNA from the Pfizer COVID-19 vaccine can enter human liver cells and convert to DNA as quickly as six hours after receiving a dose. A cancer vaccine seemed a far-fetched idea just a few years ago, but now the shots exist and are gaining steam in the biotech community. That is why it is impossible to alter your DNA with mRNA vaccines. The vaccine was administered in different amounts and for different lengths of time. Salesforce Reportedly Pays Matthew McConaughey $10 Million A Year Despite Massive Employee Layoffs Last Month, The Boring Company CEO Is Set To be The Next CEO Of Twitter, OH city violates state pre-emption, carjackings explode in NOLA, Canada hates US gun laws. Unauthorized use of these marks is strictly prohibited. We saw that there was DNA converted from the vaccine's mRNA in the host cells we studied. 2021 Dec 22;9(3):e0116221. Webpfizer vaccine become dna in liver cells 449M views Discover short videos related to pfizer vaccine become dna in liver cells on TikTok. MR: There is no reason for anyone to change their decision to take the vaccine based on this study. CMAJ. The study tested whether the vaccines mRNA could be converted to DNA, and found that this was the case in certain lab-altered liver cell lines under experimental conditions. This means that what is seen in these cells may not be representative of what would happen in non-cancerous liver cells (or even a different line of cancerous liver cells). https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support). Click here:\rhttps://www.drbeen.com/yt-special-p/\r\rWant to support this work? But studies are showing that is not the case. In the March 2022 issue of Parents PACK, we discussed some common misconceptions about science and scientists, and in the April 2022 issue, we discussed some surprising findings that were initially not believed but were ultimately proven to change our previously established understanding of science. Once the string of amino acids is created in the cell, chemical and physical forces, such as the charges and shapes of the amino acids in the sequence as well as other factors in the cellular environment, cause the newly formed protein to fold into a 3D shape. Knowing that it is theoretically possible for RNA from a virus or RNA from a vaccine to be incorporated into a cell line in a test tube is very, very different from knowing whether that cell would then survive the bodys immune system and if it did survive the bodys immune system, would make any difference, Strain said. RNA is closely related to DNA, and one type, called messenger RNA or mRNA, sends instructions to the cell for different purposes. Its precisely what health experts and fact-checkers said for more than a year could not occur. COVID-19 Vaccines (Pfizer-BioNTech and Moderna) How They Work; Happy New Year 2021! This is important for two reasons; both of which were acknowledged by the authors. PCR on genomic DNA of Huh7 cells exposed to BNT162b2 amplified the DNA sequence unique to BNT162b2. If such DNA had been incorporated into the genome, as suggested in the false claims, the fear is that it could potentially alter cell function or lead to cancer in certain cases. All quotes delayed a minimum of 15 minutes. No added sugar, full of protein and chocolate! The messenger RNA (mRNA) from Pfizer s COVID-19 Brighter days are ahead and a vaccine is coming! If you dont have time (or interest) in reviewing the primary source of the information, it is often best to let the information die in your feed or your inbox. WebThis leads to immune responses that ultimately destroy those cells. Whether our results are true for other cell types in humans, or if they are specific to mRNA vaccines, are among many questions for further research. J. Med. The most delicious sticker pack has been created for theolivemagazine.grcommunity on Rakuten Viber, Man dressed as giant penis arrested in Rio de Janeiro carnival, Three Greek destinations in the top 20 for holidays in Europe in 2023, Elon Musk Recommends Investing In Physical Things Here Are 3 Physical Assets That Perform Well During High Inflation, Zlatans first Padel club to open in Greece, NASA confirms half-ton meteor crashed in South Texas (video), The State of Democracy Where is Greece (infographic), The Worlds Oldest Populations Where is Greece? In the case of Covid shots, the vaccines from Moderna and Pfizer ( PFE )/BioNTech introduce a single spike protein. Get weekly and/or daily updates delivered to your inbox. WebSkip to topic navigation. The study, conducted by researchers at Lund University in Sweden and published in a peer-reviewed journal, investigated the effect of Pfizers mRNA COVID-19 vaccine on a human cell line that was derived from liver cancer tissue. Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc. The https:// ensures that you are connecting to the Likewise, the Results section has five sentences. Safety and Immunogenicity of Two RNA-Based COVID-19 Vaccine Candidates. These tools for evaluating information may be useful: Categories: MR: These findings were observed in petri dishes under experimental conditions, but we do not yet know if the converted DNA is integrated into the cells' DNA in the genomeand if so, if it has any consequences. This document is subject to copyright. Salesforce has already slashed 8,000 workers from its ranks this year. The antibody binds to the pathogen, but instead of blocking it from entering cells, it facilitates entry of the pathogen into cells. Whether the findings of the study will occur in living organisms or if the DNA converted from the vaccines mRNA will integrate with the cells genome is unknown. PCR primer set used to detect mRNA level and reverse-transcription of BNT162b2. DETAILS - Pfizer Vaccine Becomes DNA in The Human Liver Cells Huh7. MR: These findings were observed in petri dishes under experimental conditions, but we do not yet know if the converted DNA is integrated into the cells' DNA in the genome - and if so, if it has any consequences. Why liver cells and why the specific dose? Our publication is the first in vitro study on the conversion of mRNA vaccine into DNA, inside cells of human origin. Three other points about this paper are worth noting: Misclassification of study and logical fallacies (hasty generalization and appeal to ignorance). Parents PACK. ADE is a condition in which the antibodies against a pathogen increase the ability of the pathogen to get into cells. BNT162b2 mRNA is reverse transcribed intracellularly into DNA as fast as 6 [hours] after BNT162b2 exposure.. YDM: A previous study from MIT has indicated that the SARS-CoV-2 virus mRNA can be converted to DNA and integrated into the human genome. government site. Its precisely what health experts and fact-checkers said for more than a year could not occur. World Health Organization Coronavirus (COVID-19) Dashboard. You should not consider the information in this site to be specific, professional medical advice for your personal health or for your family's personal health. Our COVID-19 vaccine does not alter the DNA sequence of a human cell, a Pfizer spokesperson told The Epoch Times in an email. J Transl Autoimmun. 41.1M. Link to the publication in Molecular Biology: Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line. In the August 2022 James Gill paper titled Autopsy Histopathologic Cardiac Findings in 2 adolescents following the second COVID-19 vaccine dose, two teenage 19.9M. The more virus in a sample, the fewer cycles it would take to detect RNA. Two people in their 60s who received the shot were diagnosed with Guillain-Barre syndrome, out of about 20,000 vaccine recipients who participated in Pfizers Phase 3 Selena Gomez. 3401 Civic Center Blvd. Serves: 4 Prep. The mRNA vaccines are entirely synthetic using lab synthesized RNA and lipid nanoparticles for delivery. Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults. In part III of this series, we will dive more deeply into some of the things to look for when evaluating claims about a specific study. Huh7 cells were exposed to BNT162b2, and quantitative PCR was performed on RNA extracted from the cells. Lund University addressed the misinterpretations circulating on social media (here), featuring the authors of the study, Associate Professor Yang de Marinis and Professor Magnus Rasmussen. MR: The study was performed on human liver cells from one cell line cell cultures used for research purposes. (In-vitro Swedish Study) An accepted and published Swedish study demonstrates for the Privacy policy At the heart of the misconceptions about this paper is figure 1, which shows viral shedding among vaccinated (green) and unvaccinated (red) individuals. The experiment was conducted in a petri dish and aimed to answer the question of whether the mRNA in the vaccine could be converted to DNA. Noting: Misclassification of study and logical fallacies ( hasty generalization and appeal to ignorance ) points! Work ; Happy new year 2021 sequence unique to BNT162b2 amplified the DNA sequence of a human being BNT162b2 the. Antibody binds to the mRNA vaccines, as the authors pointed out expression... To refer to the pathogen to get into cells the new study from the Lund University doi:.. Inside cells of human origin ) were evaluated for liver transplantation because of persistent jaundice, hepatic insufficiency and/or! 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